INTRANASAL DELIVERY OF A CHIMPANZEE ADENOVIRUS VECTOR EXPRESSING A PRE-FUSION SPIKE (BV-ADCOV-1) PROTECTS GOLDEN SYRIAN HAMSTERS AGAINST SARS-COV-2 INFECTION

We evaluated the immunogenicity and protective ability of a chimpanzee replication-deficient adenovirus vectored COVID-19 vaccine (BV-AdCoV-1) expressing a stabilized pre-fusion SARS-CoV-2 spike glycoprotein in golden Syrian hamsters.Intranasal administration of BV-AdCoV-1 elicited strong humoral and cellular immunity in the animals.Furthermore, va

This article explores the relationship between violence, law and borders by analyzing Storage both the violence at the borders and the violence of the borders.In both cases, the author states that violence exerted by means of law, as well as migratory and asylum policies, threaten the universal human rights of the most Shimmer Walls vulnerable peop

Abstract Background Interim analysis of accumulating trial data is important to protect participant safety during randomized controlled trials (RCTs).Data Monitoring Committees (DMCs) often undertake such analyses, but their widening role may lead to extended use of interim analysis Backpacks or recommendations that could potentially bias trial res

Solving environmental and social challenges such as climate change requires a shift from our current non-renewable manufacturing model to a sustainable bioeconomy.To lower carbon emissions in the production of fuels and chemicals, plant biomass feedstocks can replace petroleum using microorganisms as biocatalysts.The anaerobic thermophile Clostridi

Background: Alcohol dependence has Jumpsuits become a major public health problem with many implications on the lives of dependents and their families.Objectives: The objectives of this study is to ascertain the enabling factors to seek medical help and continue behavior change among alcohol dependents and to assess the perceptions of health-care p